Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration.

@article{Lmmermann2009Cdc42dependentLE,
  title={Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration.},
  author={Tim L{\"a}mmermann and Joerg Renkawitz and Xunwei Wu and Karin Hirsch and Cord Brakebusch and Michael Sixt},
  journal={Blood},
  year={2009},
  volume={113 23},
  pages={5703-10}
}
Mature dendritic cells (DCs) moving from the skin to the lymph node are a prototypic example of rapidly migrating amoeboid leukocytes. Interstitial DC migration is directionally guided by chemokines, but independent of specific adhesive interactions with the tissue as well as pericellular proteolysis. Instead, the protrusive flow of the actin cytoskeleton… CONTINUE READING