Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells


Cells lining the kidney proximal tubule (PT) respond to acute changes in glomerular filtration rate and the accompanying fluid shear stress (FSS) to regulate reabsorption of ions, glucose, and other filtered molecules and maintain glomerulotubular balance. Recently, we discovered that exposure of PT cells to FSS also stimulates an increase in apical… (More)
DOI: 10.14814/phy2.13460

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