Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans

@inproceedings{Senn2012Cdc28PA,
  title={Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans},
  author={Heather Senn and Rebecca S Shapiro and Leah E Cowen},
  booktitle={Molecular biology of the cell},
  year={2012}
}
The trimorphic fungus Candida albicans is the leading cause of systemic candidiasis, a disease with poor prognosis affecting immunocompromised individuals. The capacity of C. albicans to transition between morphological states is a key determinant of its ability to cause life-threatening infection. Recently the molecular chaperone heat shock protein 90 (Hsp90) was implicated as a major regulator of temperature-dependent C. albicans morphogenesis; compromising Hsp90 function induces… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 74 references

Similar Papers

Loading similar papers…