Cdc 123 and Checkpoint Forkhead Associated with RING Proteins Control the Cell Cycle by Controlling eIF 2 Abundance *

  • CCAGG, TTATGTTCGGTATATACAAGTATGTAGAG, +3 authors ATATGTCTACTAATACTGTTCCCTC
  • Published 2004
Eukaryotic initiation factor 2 (eIF2) is a central regulator of translational initiation in times of growth and times of stress. Here we discovered three new conserved regulators of eIF2 in Saccharomyces cerevisiae. cdc123, homolog of mammalian D123, is a new cell division cycle mutant with a G2 delay at permissive temperature and a terminal, mating… CONTINUE READING