CcsBA is a cytochrome c synthetase that also functions in heme transport.


Little is known about trafficking of heme from its sites of synthesis to sites of heme-protein assembly. We describe an integral membrane protein that allows trapping of endogenous heme to elucidate trafficking mechanisms. We show that CcsBA, a representative of a superfamily of integral membrane proteins involved in cytochrome c biosynthesis, exports and… (More)
DOI: 10.1073/pnas.0903132106


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