Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division.

@article{Pevorovsk2009Cbf11AC,
  title={Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division.},
  author={Martin Převorovsk{\'y} and Tom{\'a}s Grousl and Jana Stanurov{\'a} and Jan Rynes and Wolfgang Nellen and Franti{\vs}ek Půta and Petr Folk},
  journal={Experimental cell research},
  year={2009},
  volume={315 8},
  pages={1533-47}
}
The CSL (CBF1/RBP-Jkappa/Suppressor of Hairless/LAG-1) family is comprised of transcription factors essential for metazoan development, mostly due to their involvement in the Notch receptor signaling pathway. Recently, we identified two novel classes of CSL genes in the genomes of several fungal species, organisms lacking the Notch pathway. In this study, we characterized experimentally cbf11+ and cbf12+, the two CSL genes of Schizosaccharomyces pombe, in order to elucidate the CSL function in… CONTINUE READING
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