Ca~(2+)-activated Cl~- channels and pulmonary hypertension induced by high pulmonary blood flow

@inproceedings{Yusheng2012Ca2activatedCC,
  title={Ca~(2+)-activated Cl~- channels and pulmonary hypertension induced by high pulmonary blood flow},
  author={Pang Yu-sheng},
  year={2012}
}
Pulmonary hypertension induced by high pulmonary blood flow involves a variety of complex mechanisms,including endothelial damage,pulmonary artery smooth muscle relaxation-contraction disorder and vascular remodeling.Besides,the factor of ion channels in pulmonary artery smooth muscle cells is also highly correlated to vasoconstriction.In recent years,many studies have shown that activation of Ca2+-activated Cl-channels is responsible for the membrane depolarization of pulmonary artery smooth… CONTINUE READING