Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound.

@article{Gruber2014CavitationTO,
  title={Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound.},
  author={Matthew J. Gruber and Kenneth B. Bader and Christy K. Holland},
  journal={The Journal of the Acoustical Society of America},
  year={2014},
  volume={135 2},
  pages={
          646-53
        }
}
Ultrasound contrast agents (UCAs) can be employed to nucleate cavitation to achieve desired bioeffects, such as thrombolysis, in therapeutic ultrasound applications. Effective methods of enhancing thrombolysis with ultrasound have been examined at low frequencies (<1 MHz) and low amplitudes (<0.5 MPa). The objective of this study was to determine cavitation thresholds for two UCAs exposed to 120-kHz ultrasound. A commercial ultrasound contrast agent (Definity(®)) and echogenic liposomes were… CONTINUE READING
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