Cavin family proteins and the assembly of caveolae.

  title={Cavin family proteins and the assembly of caveolae.},
  author={Oleksiy Kovtun and Vikas A Tillu and Nicholas Ariotti and Robert G. Parton and Brett M Collins},
  journal={Journal of cell science},
  volume={128 7},
Caveolae are an abundant feature of the plasma membrane in many cells. Until recently, they were generally considered to be membrane invaginations whose formation primarily driven by integral membrane proteins called caveolins. However, the past decade has seen the emergence of the cavin family of peripheral membrane proteins as essential coat components and regulators of caveola biogenesis. In this Commentary, we summarise recent data on the role of cavins in caveola formation, highlighting… CONTINUE READING
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