Cavernous sinus sampling is highly accurate in distinguishing Cushing's disease from the ectopic adrenocorticotropin syndrome and in predicting intrapituitary tumor location.

@article{Graham1999CavernousSS,
  title={Cavernous sinus sampling is highly accurate in distinguishing Cushing's disease from the ectopic adrenocorticotropin syndrome and in predicting intrapituitary tumor location.},
  author={Kylie Graham and Mary Samuels and Gary M. Nesbit and David M. Cook and Owen O'Neill and Stanley L. Barnwell and Donald L Loriaux},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 5},
  pages={1602-10}
}
Inferior petrosal sinus sampling (IPSS) is used to distinguish pituitary Cushing's disease from occult cases of the ectopic ACTH syndrome, but is limited in that it requires the use of ovine CRH (oCRH) and is not highly accurate at predicting the intrapituitary location of tumors. This study was designed to determine whether cavernous sinus sampling (CSS) is as safe and accurate as IPSS, whether CSS can eliminate the need for oCRH stimulation, and whether CSS can accurately predict the… CONTINUE READING
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