Caveolin-3 regulates the Volume-Regulated Anion Channel in Mouse Ventricular Cells

@inproceedings{Yamamoto2011Caveolin3RT,
  title={Caveolin-3 regulates the Volume-Regulated Anion Channel in Mouse Ventricular Cells},
  author={Shintaro Yamamoto and S. Kita and T. Iyoda and Toshiki Yamada and T. Iwamoto},
  year={2011}
}
Caveolae are small invaginated microdomains located with a variety of signal transduction molecules on the plasma membrane. Recent reports showed that the knockout mice of a muscle-specific protein caveolin-3 (Cav-3 KO), a principal component of the caveolae in heart, displayed an enlargement of ventricular cells. Volume-regulated outwardly rectifying anion channel (VRAC) is activated by membrane stretch, and play a significant role in cell volume regulation in cardiac cells. However, it is… Expand
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