BACKGROUND AND PURPOSE
Resistance of pancreatic ductal adenocarcinoma (PDAC) to chemo- and radiotherapy is a major obstacle. The integral membrane protein Caveolin-1 (Cav-1) has been suggested as a potent target in human pancreatic carcinoma cells.
MATERIALS AND METHODS
Human pancreatic tumor cells were examined in a three-dimensional (3D) cell culture… (More)