Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells.

@article{FelleyBosco2002Caveolin1mediatedPR,
  title={Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells.},
  author={Emanuela Felley-Bosco and Florent Bender and Andrew F. G. Quest},
  journal={Biological research},
  year={2002},
  volume={35 2},
  pages={169-76}
}
Reactive oxygen species are now widely recognized as important players contributing both to cell homeostasis and the development of disease. In this respect nitric oxide (NO) is no exception. The discussion here will center on regulation of the inducible form of nitric oxide synthase (iNOS) for two reasons. First, only iNOS produces micromolar NO concentrations, amounts that are high by comparison with the picomolar to nanomolar concentrations resulting from Ca2(+)-controlled NO production by… CONTINUE READING

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