Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia.

@article{Frank2004Caveolin1AC,
  title={Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia.},
  author={Philippe G Frank and Michael Phillip Lisanti},
  journal={Current opinion in lipidology},
  year={2004},
  volume={15 5},
  pages={
          523-9
        }
}
PURPOSE OF REVIEW Caveolae are 50-100 nm cell surface plasma membrane invaginations observed in terminally differentiated cells. They are characterized by the presence of the protein marker caveolin-1. Caveolae and caveolin-1 are present in almost every cell type that has been implicated in the development of an atheroma. These include endothelial cells, macrophages, and smooth muscle cells. Caveolae and caveolin-1 are involved in regulating several signal transduction pathways and processes… CONTINUE READING
Highly Cited
This paper has 79 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

Caveolin-1 expression is associated with plaque formation in hypercholesterolemic rabbits.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society • 2006
View 12 Excerpts
Highly Influenced

79 Citations

01020'08'11'14'17
Citations per Year
Semantic Scholar estimates that this publication has 79 citations based on the available data.

See our FAQ for additional information.