Caveolar Uptake and Endothelial-Protective Effects of Nanostructured Lipid Carriers in Acid Aspiration Murine Acute Lung Injury

Nanostructured lipid carriers (NLC), nanosized phospholipids/triglyceride particles developed for drug delivery, are considered biologically inactive. We assessed the efficacy of unloaded NLC as experimental treatment for acute lung injury (ALI). To induce ALI, C57Black/6 male mice received intratracheal injections of HCl or saline; A single dose of 16 mg… CONTINUE READING