Caveolae compartmentalization of heme oxygenase-1 in endothelial cells.

@article{Kim2004CaveolaeCO,
  title={Caveolae compartmentalization of heme oxygenase-1 in endothelial cells.},
  author={Hong Pyo Kim and Xue Wang and Ferruccio Galbiati and Stefan W. Ryter and Augustine M. K. Choi},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2004},
  volume={18 10},
  pages={1080-9}
}
The heme oxygenase (HO) and nitric oxide synthase (NOS) enzymes generate the gaseous signaling molecules carbon monoxide (CO) and nitric oxide, respectively. Constitutive NOSs localize to caveolae, and their activities are modulated by caveolin-1. Nothing is known of the localization of the inducible heme oxygenase-1 (HO-1) in plasma membrane caveolae. Thus… CONTINUE READING