Causes of limited survival of microencapsulated pancreatic islet grafts.

@article{Groot2004CausesOL,
  title={Causes of limited survival of microencapsulated pancreatic islet grafts.},
  author={Martijn de Groot and Theo A. Schuurs and Reinout van Schilfgaarde},
  journal={The Journal of surgical research},
  year={2004},
  volume={121 1},
  pages={141-50}
}
Successful transplantation of pancreatic tissue has been demonstrated to be an efficacious method of restoring glycemic control in type 1 diabetic patients. To establish graft acceptance patients require lifelong immunosuppression, which in turn is associated with severe deleterious side effects. Microencapsulation is a technique that enables the transplantation of pancreatic islets in the absence of immunosuppression by protecting the islet tissue through a mechanical barrier. This protection… CONTINUE READING