Causes of extreme fatigue in underperforming athletes - a synthesis of recent hypotheses and reviews

@article{RobsonAnsley2006CausesOE,
  title={Causes of extreme fatigue in underperforming athletes - a synthesis of recent hypotheses and reviews},
  author={P. Robson-Ansley and L. Smith},
  journal={South African Journal of Sports Medicine},
  year={2006},
  volume={18},
  pages={108-114}
}
The underperformance syndrome (UPS), previously known as the overtraining syndrome (OTS), has been defined as a persistent decrement in athletic performance capacity despite 2 weeks of relative rest. Clinical research has suggested that cytokines play a key role in fatigue in disease and chronic fatigue syndrome. Furthermore, it has recently been demonstrated that exogenous administration of interleukin-6 (IL-6) increases the sensation of fatigue during exercise. In light of current cytokine… Expand
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