Causes of developmental failure of in-vitro matured rhesus monkey oocytes: impairments in embryonic genome activation.

@article{Schramm2003CausesOD,
  title={Causes of developmental failure of in-vitro matured rhesus monkey oocytes: impairments in embryonic genome activation.},
  author={R. Dee Schramm and Ann Marie Paprocki and Catherine A. Vandevoort},
  journal={Human reproduction},
  year={2003},
  volume={18 4},
  pages={826-33}
}
BACKGROUND Understanding the causes of developmental failure of in-vitro matured primate oocytes may lead to viable strategies for improving their developmental competence. The aims of this study were to determine whether the timely onset of embryonic genome activation among individual blastomeres of preimplantation macaque embryos is impaired by in-vitro maturation (IVM) of oocytes and whether these impairments are associated with developmental failure during the embryonically controlled… CONTINUE READING

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