Contemporary views on human aging and longevity
The aim of this article is to present and compare the views of both parties in the dispute, based on the results of some recent experimental studies, and the contemporary knowledge of selected major aspects of human aging and longevity.
Anticardiolipin antibodies and recurrent spontaneous abortion in Brazilian women
- Medicine, Biology
The frequency of anti-cardiolipin antibodies (aCL) was elevated among patients with a history of RSA, especially those having higher number of fetal losses, and among women with at least two spontaneous abortions, the mean number of abortions was not significantly different between those reagent for aCL and those non reagent.
Reproductive mode and the shifting arenas of evolutionary conflict
- PsychologyAnnals of the New York Academy of Sciences
This work focuses on four major categories of animal reproductive mode (broadcast spawning, egg laying, live bearing, and live bearing with matrotrophy) and identifies the shared phenotypes or traits over which conflict is expected, and reviews the empirical literature for evidence of their occurrence.
Testing for post‐copulatory selection for major histocompatibility complex genotype in a semi‐free‐ranging primate population
- BiologyAmerican journal of primatology
Comparing parental and offspring haplotypes may be a useful approach to test for post‐copulatory selection when matings cannot be observed, as is the case in many study systems, but it will be extremely difficult to determine conclusively whether post‐Copulatory selection mechanisms for MHC genotype exist, particularly if the effect sizes are small.
Relationship between filial cannibalism, egg energetic content and parental condition in the flagfish
- BiologyAnimal Behaviour
Suicidal function of DNA methylation in age-related genome disintegration
- BiologyAgeing Research Reviews
Do placental species abort offspring? Testing an assumption of the Trexler–DeAngelis model
The results suggest P. monacha responds to low food by sacrificing reproduction to maintain lipids, while P. prolifica maintains reproduction at the expense of lipids.
SHOWING 1-10 OF 10 REFERENCES
Frequency and Origin of Chromosome Abnormalities in Man
During the past 25 years human cytogenetics has changed from a highly specialized academic discipline restricted to only a few institutions to a rapidly expanding area of research and routine…
Differences in Risk of Insulin-Dependent Diabetes in Offspring of Diabetic Mothers and Diabetic Fathers
It is concluded that IDDM is transmitted less frequently to the offspring of diabetic women than to those of diabetic men and more study is required to determine whether this difference reflects a genetic mechanism or, instead, se...
Screening for Gestational Diabetes: Optimum Timing and Criteria for Retesting
The purpose of this study was to elucidate the optimum time to test for diabetes during gestation, the indication for retesting, and the predictive value of a positive screening test for a large (>4000 g) infant.
Major histocompatibility complex antigens, maternal and paternal immune responses, and chronic habitual abortions in humans.
- MedicineAmerican journal of obstetrics and gynecology
The results indicate that MHC homozygosity between spouses is associated with postfertilization pregnancy wastage in humans.
HLA-DR locus and maternal-foetal relation.
- BiologyTissue antigens
The results showed that in couples with more than two idiopathic repeated abortions, there is no significant increase in the HLA antigen sharing couples, but the affected couples were able to observe asignificant increase in HLA-DR antigen sharing as regards the control couples.
Fetal mortality in oral cleft families (IX): factors relating to the occurrence of sporadic clefts
- MedicineClinical genetics
Pedigree data on 854 probands with cleft lip and/or cleft palate from the State of Indiana are presented and among features of special interest are an excess of bilateral CLP and a significantly greater number of older mothers and fathers than in the general population.
Preferential transmission of diabetic alleles within the HLA gene complex.
- Medicine, BiologyThe New England journal of medicine
The data suggest that differential parental transmission of the HLA-DR4-linked diabetes-predisposing allele may explain the higher risk of diabetes among children of diabetic fathers than among those of diabetic mothers.
What maintains the frequencies of human genetic diseases?