Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review.

@article{Wamberg2015CausesOV,
  title={Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review.},
  author={Louise Wamberg and Steen B\onl\okke Pedersen and Lars Rejnmark and Bj\orn Richelsen},
  journal={Current obesity reports},
  year={2015},
  volume={4 4},
  pages={
          429-40
        }
}
Obese subjects are often characterized by low plasma 25-hydroxy-vitamin D (25OHD) levels. Many explanations for this association have been proposed. Low plasma 25OHD is associated with obesity-related comorbidities such as insulin resistance, type 2 diabetes mellitus, and low-grade inflammation. In this review, we discuss the proposed mechanisms for low 25OHD in obesity and explore the results of recent RCTs on vitamin D (VD) supplementation on obesity and its metabolic complications such as… CONTINUE READING
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