Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review

  title={Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review},
  author={L. Wamberg and S. Pedersen and L. Rejnmark and B. Richelsen},
  journal={Current Obesity Reports},
  • L. Wamberg, S. Pedersen, +1 author B. Richelsen
  • Published 2015
  • Medicine
  • Current Obesity Reports
  • Obese subjects are often characterized by low plasma 25-hydroxy-vitamin D (25OHD) levels. Many explanations for this association have been proposed. Low plasma 25OHD is associated with obesity-related comorbidities such as insulin resistance, type 2 diabetes mellitus, and low-grade inflammation. In this review, we discuss the proposed mechanisms for low 25OHD in obesity and explore the results of recent RCTs on vitamin D (VD) supplementation on obesity and its metabolic complications such as… CONTINUE READING
    36 Citations
    Vitamin D Deficiency: Consequence or Cause of Obesity?
    • 12
    • PDF
    Vitamin D, sub-inflammation and insulin resistance. A window on a potential role for the interaction between bone and glucose metabolism
    • 44
    • Highly Influenced
    Role of vitamin D in insulin resistance in obese individuals
    • 1
    • PDF
    Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.
    • 1
    Vitamin D metabolism in human adipose tissue: could it explain low vitamin D status in obesity?
    • 9
    • Highly Influenced
    Vitamin D Is Inversely Related to Obesity: Cross-Sectional Study in a Small Cohort of Serbian Adults
    • 9


    Vitamin D: a new player in non-alcoholic fatty liver disease?
    • 89
    Decreased bioavailability of vitamin D in obesity.
    • 2,656
    • PDF
    Vitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markers.
    • 491
    • PDF
    Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis.
    • M. Holick
    • Medicine
    • The American journal of clinical nutrition
    • 2004
    • 1,555
    • PDF
    The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults.
    • 647
    • PDF