Causes and outcome of seizures in liver transplant recipients.

  title={Causes and outcome of seizures in liver transplant recipients.},
  author={Eelco F. M. Wijdicks and David J. Plevak and Russell H. Wiesner and Jeffery L. Steers},
  volume={47 6},
Previous studies found that seizures in orthotopic liver transplantation (OLT) herald a catastrophic neurologic event, but the studies were done of patients who later died and came to autopsy. We studied 630 OLT patients. Laboratory values, electroencephalography, neuroimaging, and levels of cyclosporine or FK506 were reviewed. Neurotoxicity from immunosuppression was considered a trigger for seizures when toxic blood level or increases > or = to 100% were documented, or when white matter… CONTINUE READING


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