Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system

  title={Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system},
  author={Douglas L. Feinstein and Sergey Kalinin and David Braun},
  journal={Journal of Neurochemistry},
Aside from its roles in as a classical neurotransmitter involved in regulation of behavior, noradrenaline (NA) has other functions in the CNS. This includes restricting the development of neuroinflammatory activation, providing neurotrophic support to neurons, and providing neuroprotection against oxidative stress. In recent years, it has become evident that disruption of physiological NA levels or signaling is a contributing factor to a variety of neurological diseases and conditions including… 

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