Causal Influence of Visual Cues on Hippocampal Directional Selectivity

  title={Causal Influence of Visual Cues on Hippocampal Directional Selectivity},
  author={Lavanya Acharya and Zahra M. Aghajan and Cliff Vuong and Jason J Moore and Mayank R. Mehta},
Hippocampal neurons show selectivity with respect to visual cues in primates, including humans, but this has never been found in rodents. To address this long-standing discrepancy, we measured hippocampal activity from rodents during real-world random foraging. Surprisingly, ∼ 25% of neurons exhibited significant directional modulation with respect to visual cues. To dissociate the contributions of visual and vestibular cues, we made similar measurements in virtual reality, in which only visual… CONTINUE READING
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