Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome

  title={Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome},
  author={Michael H. Bloch and James Frederick Leckman and Hongtu Zhu and Bradley S. Peterson},
  pages={1253 - 1258}
Background: Most children with Tourette syndrome (TS) experience a marked decline in the severity of tic symptoms during adolescence. Currently no clinical measures can predict whose tic symptoms will persist into adulthood. Previous cross-sectional imaging studies have identified reduced caudate nucleus volumes in subjects with TS. Objective: To evaluate whether caudate nucleus volumes in childhood can predict the severity of tic or obsessive–compulsive symptoms at follow-up in early adulthood… 

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