Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression.

@article{Naismith2002CaudateNV,
  title={Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression.},
  author={Sharon L Naismith and Ian B. Hickie and Philip B. Ward and Keelin Turner and Elizabeth M Scott and Craig L Little and Philip B. Mitchell and Kay Wilhelm and Gordon Parker},
  journal={The American journal of psychiatry},
  year={2002},
  volume={159 12},
  pages={2096-8}
}
OBJECTIVE The authors sought to determine whether caudate nucleus volumes or specific genotypes predict psychomotor slowing in older persons with depression. METHOD Forty-seven persons with depression (mean age=51.8 years, SD=12.4) and 20 healthy volunteers (mean age=56.1 years, SD=9.8) underwent clinical assessments, a neuropsychological test of psychomotor speed (part A of the Trail Making Test), high-resolution magnetic resonance imaging scans, and genotyping for the apolipoprotein E… CONTINUE READING