Caudal dysplasia sequence: severe phenotype presenting in offspring of patients with gestational and pregestational diabetes.

@article{Versiani2004CaudalDS,
  title={Caudal dysplasia sequence: severe phenotype presenting in offspring of patients with gestational and pregestational diabetes.},
  author={Beatriz Ribeiro Versiani and Enid F Gilbert-Barness and Liane de Rosso Giuliani and Luiz C{\'e}sar Peres and Jo{\~a}o Monteiro de Pina-Neto},
  journal={Clinical dysmorphology},
  year={2004},
  volume={13 1},
  pages={1-5}
}
The association of maternal diabetes mellitus and congenital anomalies is well established. Children of insulin-dependent diabetic women have an increased risk of congenital malformations, especially major multiorgan defects. The cardiovascular, central nervous, gastrointestinal, genitourinary and musculoskeletal are the most affected body systems. Studies also show that offspring of women with gestational diabetes (specially those with fasting hyperglycaemia) tend to have higher rates of… CONTINUE READING

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