Cationic vectors in ocular drug delivery.

  title={Cationic vectors in ocular drug delivery.},
  author={Laura Rabinovich-Guilatt and Patrick Couvreur and Gregory Lambert and Catherine Dubernet},
  journal={Journal of drug targeting},
  volume={12 9-10},
Despite extensive research in the field, the major problem in the ocular drug delivery domain still is rapid precorneal drug loss and poor corneal permeability. One of the approaches recently developed is the drug incorporation into cationic submicronic vectors which exploit the negative charges present at the corneal surface for increased residence time and penetration. This review will focus on the formulation of three main representative cationic colloids developed for ophthalmic delivery… CONTINUE READING

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