Cationic surfactants derived from lysine: effects of their structure and charge type on antimicrobial and hemolytic activities.

@article{Colomer2011CationicSD,
  title={Cationic surfactants derived from lysine: effects of their structure and charge type on antimicrobial and hemolytic activities.},
  author={Aurora Colomer and Aurora Pinazo and M. A. Manresa and Mar{\'i}a Pilar Vinardell and Montserrat Mitjans and Mar{\'i}a Rosa Infante and Lourdes P{\'e}rez},
  journal={Journal of medicinal chemistry},
  year={2011},
  volume={54 4},
  pages={989-1002}
}
Three different sets of cationic surfactants from lysine have been synthesized. The first group consists of three monocatenary surfactants with one lysine as the cationic polar head with one cationic charge. The second consists of three monocatenary surfactants with two amino acids as cationic polar head with two positive charges. Finally, four gemini surfactants were synthesized in which the spacer chain and the number and type of cationic charges have been regulated. The micellization process… CONTINUE READING

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