Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises.

@article{Karmali2007CationicLA,
  title={Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises.},
  author={Priya Prakash Karmali and Arabinda Chaudhuri},
  journal={Medicinal research reviews},
  year={2007},
  volume={27 5},
  pages={
          696-722
        }
}
The clinical success of gene therapy is critically dependent on the development of efficient and safe gene delivery reagents, popularly known as "transfection vectors." The transfection vectors commonly used in gene therapy are mainly of two types: viral and non-viral. The efficiencies of viral transfection vectors are, in general, superior to their non-viral counterparts. However, the myriads of potentially adverse immunogenic aftermaths associated with the use of viral vectors are… CONTINUE READING

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