Cationic liposome-mediated delivery of siRNAs in adult mice.

@article{Sioud2003CationicLD,
  title={Cationic liposome-mediated delivery of siRNAs in adult mice.},
  author={Mouldy Sioud and Dag Reidar S\orensen},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={312 4},
  pages={1220-5}
}
RNA interference mediated by small interfering RNAs (siRNAs) is a powerful tool for dissecting gene function and drug target validation. siRNAs can be synthesized in large quantities and thus can be used to analyze a large number of sequences emerging from genome projects in a cost-effective manner. However, the major obstacle to the use of siRNAs as… CONTINUE READING