Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment.

@article{Mader2006CationicAP,
  title={Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment.},
  author={Jamie S Mader and David W. Hoskin},
  journal={Expert opinion on investigational drugs},
  year={2006},
  volume={15 8},
  pages={933-46}
}
Cancer treatment by conventional chemotherapy is hindered by toxic side effects and the frequent development of multi-drug resistance by cancer cells. Cationic antimicrobial peptides (CAPs) are a promising new class of natural-source drugs that may avoid the shortcomings of conventional chemotherapy because certain CAPs exhibit selective cytotoxicity against a broad spectrum of human cancer cells, including neoplastic cells that have acquired a multi-drug-resistant phenotype. Tumour cell… CONTINUE READING

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