Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens.

@article{LaRock2015CationicAP,
  title={Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens.},
  author={Christopher N LaRock and Victor Nizet},
  journal={Biochimica et biophysica acta},
  year={2015},
  volume={1848 11 Pt B},
  pages={
          3047-54
        }
}
Cationic antimicrobial peptides (CAMPs) are critical front line contributors to host defense against invasive bacterial infection. These immune factors have direct killing activity toward microbes, but many pathogens are able to resist their effects. Group A Streptococcus, group B Streptococcus and Streptococcus pneumoniae are among the most common pathogens of humans and display a variety of phenotypic adaptations to resist CAMPs. Common themes of CAMP resistance mechanisms among the… CONTINUE READING

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