Cation specificity and pharmacological properties of the Ca2+-dependent K+ channel of rat cortical collecting ducts

@article{Schlatter1993CationSA,
  title={Cation specificity and pharmacological properties of the Ca2+-dependent K+ channel of rat cortical collecting ducts},
  author={Eberhard Schlatter and Markus Bleich and J{\"u}rgen Hirsch and U. Markstahler and U. Fr{\"o}be and Rainer Greger},
  journal={Pfl{\"u}gers Archiv},
  year={1993},
  volume={422},
  pages={481-491}
}
The luminal membrane of principal cells of rat cortical collecting duct (CCD) is dominated by a K+ conductance. Two different K+ channels are described for this membrane. K+ secretion probably occurs via a small-conductance Ca2+-independent channel. The function of the second, large-conductance Ca2+-dependent channel is unclear. This study examines properties of this channel to allow a comparison of this K+ channel with the macroscopic K+ conductance of the CCD and with similar K+ channels from… CONTINUE READING

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