Cation selectivity of light-sensitive conductance in retinal rods

  title={Cation selectivity of light-sensitive conductance in retinal rods},
  author={K. K. C. Yau and Kei Nakatani},
Vertebrate photoreceptors respond to light by a membrane hyperpolarization which is thought to result from the decrease of a Na-selective conductance in the outer segment1–6. One hypothesis is that light increases intracellular free Ca which reversibly blocks the Na conductance7,8; at least part of this Ca is then extruded to the cell exterior by a Na–Ca exchanger at the plasma membrane9–14. We describe experiments here which show that the light-sensitive conductance in rods is also highly… CONTINUE READING


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