Cation conductance and efflux induced by polyene antibiotics in the membrane of skeletal muscle fiber.

@article{Shvinka1994CationCA,
  title={Cation conductance and efflux induced by polyene antibiotics in the membrane of skeletal muscle fiber.},
  author={N. E. Shvinka and G. Caffier},
  journal={Biophysical journal},
  year={1994},
  volume={67 1},
  pages={143-52}
}
Cation conductance and efflux induced by polyene antibiotics amphotericin B (AMB), amphotericin B methyl ester (AME), nystatin, mycoheptin, and levorin on frog isolated skeletal muscle fibers and whole sartorius muscles were investigated. Conductance was measured under current-clamp conditions using a double sucrose-gap technique. Cation efflux was studied using flame emission photometry. Some new data were obtained concerning the effects of levorin and mycoheptin on biological membranes. The… CONTINUE READING