Cation Diffusion Facilitator family: Structure and function.

@article{KolajRobin2015CationDF,
  title={Cation Diffusion Facilitator family: Structure and function.},
  author={Olga Kolaj-Robin and David R. Russell and Kevin Hayes and J. Tony Pembroke and Tewfik Soulimane},
  journal={FEBS letters},
  year={2015},
  volume={589 12},
  pages={
          1283-95
        }
}
The Cation Diffusion Facilitators (CDFs) form a family of membrane-bound proteins capable of transporting zinc and other heavy metal ions. Involved in metal tolerance/resistance by efflux of ions, CDF proteins share a two-modular architecture consisting of a transmembrane domain (TMD) and C-terminal domain (CTD) that protrudes into the cytoplasm. Discovery of a Zn²⁺ and Cd²⁺ CDF transporter from a marine bacterium Maricaulis maris that does not possess the CTD questions current perceptions… CONTINUE READING

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