Catheter-directed thrombolytic therapy for limb ischemia: current status and controversies.

  title={Catheter-directed thrombolytic therapy for limb ischemia: current status and controversies.},
  author={Mahmood Razavi and David S Lee and Lawrence Vincent Hofmann},
  journal={Journal of vascular and interventional radiology : JVIR},
  volume={15 1 Pt 1},
Absence of urokinase from the United States market for the past 4 years has resulted in increasing experience with other plasminogen activators in catheter-directed thrombolytic therapy. The differences in the pharmacologic properties and biologic behavior of these agents may translate into clinical outcomes that are distinct. Some of these manifestations can be predicted based on the existing large clinical trials in the acute myocardial infarction literature. However, because of the… CONTINUE READING

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