Cathepsin D is one of the major enzymes involved in intracellular degradation of AGE-modified proteins.

Abstract

Oxidized and cross-linked modified proteins are known to accumulate in ageing. Little is known about whether the accumulation of proteins modified by advanced glycation end products (AGEs) is due to an affected intracellular degradation. Therefore, this study was designed to determine whether the intracellular enzymes cathepsin B, cathepsin D and the 20S… (More)
DOI: 10.3109/10715762.2010.495127

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