Catharanthus alkaloids. XV. Isolation of vindolinine from C. lanceus leaves.

  title={Catharanthus alkaloids. XV. Isolation of vindolinine from C. lanceus leaves.},
  author={E M Maloney and Harry Hong Sang Fong and N. R. Farnsworth and Ralph N. Blomster and Donald J. Abraham},
  journal={Journal of pharmaceutical sciences},
  volume={57 6},
A continuing study of Catharantbus lanceus for antineoplastic alkaloids has resulted in the isolation of vindolinine (as HC1), which is reported for the first time from this plant. Perivine and yohimbine, reported previously, were also obtained in high yield. 
Effect of Rabbit Manure, VA Mycorrhiza and Bacillus sirculans on Growth, Flowering and Chemical Constituents of Periwinkle (Catharanthus roseus L.) Plants
In most cases, the combined effect between rabbit manure fertilizer and bio-fertilizer treatments on periwinkle (Catharanthus roseus) parameters was statistically significant and inoculating the plants in combination with high rate of rabbit manure and VAM and B.S. was the most effective treatments concerning growth, flowering as well as chemical constituents. Expand
Effects of three levels of mycorrhiza and four levels of planting bed on total wet and dry weight of shoots and the number of lateral branches of white periwinkle (Catharanthus alba)
The mycorrhizal type of G. interaradices (treatment m2) showed the highest significant effect on the characteristics of total wet and dry weight of shoots and the number of lateral branches in the yield of the medicinal plant of periwinkle. Expand
Organic N-fertilizer, rhizobacterial inoculation and fungal compost improve nutrient uptake, plant growth and the levels of vindoline, ajmalicine, vinblastine, catharanthine and total alkaloids in Catharanthus roseus L.
The growth and metabolism of C. roseus were significantly positively affected by the organic and biological fertilizers and the N-fertilizer improved many morphological and nutrient characteristics. Expand


Catharanthus alkaloids. X. Isolation of lanceine and vinosidine from Catharanthus lanceus roots.
In a continuing search for new biologically active entities in Catharanthus lanceus, additional work on the root (A) fraction has led to the isolation of two alkaloids, including lanceine and Vinosidine, reported from this species for the first time. Expand
Catharanthus lanceus VII. Isolation of tetrahydroalstonine, lochnerinine, and periformyline.
Details concerning the isolation of tetrahydroalstonine, lochnerinine, and the structure elucidation of periformyline, the first example of an N (b) -substituted formyl indole alkaloid to be found in nature, are presented. Expand
Structure Elucidation and Chemistry of Catharanthus Alkaloids II. Isolation and Partial Structure of Catharine, a Dimeric Indole Alkaloid From C. Zanceus and C. Roseus
A continuing study of Catharanthus lanceus alkaloid fractions, in a search for new antineoplastic alkaloids, has led to the isolation of Catharine, a dimeric indole alkaloid found previously only inExpand