Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressure.

@article{Mahapatra2008CatestatinIA,
  title={Catestatin is a novel endogenous peptide that regulates cardiac function and blood pressure.},
  author={Nitish R. Mahapatra},
  journal={Cardiovascular research},
  year={2008},
  volume={80 3},
  pages={330-8}
}
Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide that is formed endogenously by proteolytic cleavage of its precursor chromogranin A, a major protein co-stored and co-released with catecholamines from the storage vesicles in adrenal chromaffin cells and adrenergic neurons. This peptide exhibits potent catecholamine release-inhibitory activity by acting on the neuronal nicotinic acetylcholine receptor. It also stimulates histamine release from mast cells via heterotrimeric… CONTINUE READING