Categorizing and assessing negative symptoms
@article{Bucci2017CategorizingAA, title={Categorizing and assessing negative symptoms}, author={Paola Bucci and Silvana Galderisi}, journal={Current Opinion in Psychiatry}, year={2017}, volume={30}, pages={201–208} }
Purpose of review To provide a review on studies published in the last year relevant to the categorization and assessment of negative symptoms. Recent findings Recent research supported the validity of the ‘deficit/non-deficit schizophrenia’ categorization. Few studies confirmed the validity of the category ‘persistent negative symptoms’, whereas no recent study explored the validity of the category ‘predominant negative symptoms’. The two-factor structure of the negative dimension is supported…
23 Citations
EPA guidance on assessment of negative symptoms in schizophrenia
- Medicine, PsychologyEuropean Psychiatry
- 2021
This European Psychiatric Association (EPA) guidance recommends the use of persistent negative symptoms (PNS) construct in the context of clinical trials and highlights the need for further efforts to make the definition of PNS consistent across studies in order to exclude as much as possible secondary negative symptoms.
Assessment of negative symptoms in male and female schizophrenia patients using the Polish version of the Brief Negative Syndrome Scale and Self-evaluation of Negative Symptoms
- Psychology, Medicine
- 2018
The results indicate the existence of significant gender differences in the assessment of negative symptoms in three subscales of the Brief Negative Symptom Scale.
EPA guidance on treatment of negative symptoms in schizophrenia
- Psychology, MedicineEuropean Psychiatry
- 2021
Recommendations for the treatment of undifferentiated negative symptoms (including both primary and secondary negative symptoms) are provided and although it has proven difficult to formulate an evidence-based recommendation for the choice of an antipsychotic, a switch to a second-generation antipsychotics should be considered.
A large European, multicenter, multinational validation study of the Brief Negative Symptom Scale
- Psychology, MedicineEuropean Neuropsychopharmacology
- 2019
The effectiveness and safety of cariprazine in schizophrenia patients with negative symptoms and insufficient effectiveness of previous antipsychotic therapy: an observational study
- Medicine, PsychologyInternational clinical psychopharmacology
- 2021
Cariprazine significantly improved negative symptoms in schizophrenia patients in an open-label, flexible-dose, 16-week, observational study in Latvia.
Elucidating negative symptoms in the daily life of individuals in the early stages of psychosis
- Psychology, MedicinePsychological Medicine
- 2020
Overall, altered affective experience, anhedonia, social an Shedonia and asociality seem to play less of a role in the daily life of individuals in the early stages of psychosis than previously assumed.
The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors
- Psychology, MedicineEuropean Psychiatry
- 2019
Neurocognitive functioning and quality of life in patients with and without deficit syndrome of schizophrenia
- Psychology, MedicinePsychiatry Research
- 2018
Disentangling the symptoms of schizophrenia: Network analysis in acute phase patients and in patients with predominant negative symptoms
- Psychology, MedicineEuropean Psychiatry
- 2021
This network analysis suggests that symptoms of schizophrenia are differently structured in acute and PNS patients, and primary negative symptoms are better conceptualized as distinct negative symptom dimensions of the PANSS.
Long-term oral blonanserin treatment for schizophrenia: a review of Japanese long-term studies
- Psychology, MedicineAnnals of General Psychiatry
- 2021
In conclusion, blonanserin is useful for long-term treatment of chronic schizophrenic patients when the appropriate management of clinical symptoms and adverse drug reactions are applied and may possibly fit both the current real-world clinical setting and the currently recommended approach to antipsychotics.
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