Catechoserine, a new catecholate-type inhibitor of tumor cell invasion from Streptomyces sp.

@article{Igarashi2012CatechoserineAN,
  title={Catechoserine, a new catecholate-type inhibitor of tumor cell invasion from Streptomyces sp.},
  author={Yasuhiro Igarashi and Takako Iida and Takao Fukuda and Satoshi Miyanaga and Hiroaki Sakurai and Ikuo Saiki and Koji Miyanouchi},
  journal={The Journal of Antibiotics},
  year={2012},
  volume={65},
  pages={207-209}
}
Microbial natural products represent the primary resource for drug discovery, accounting for 420 000 bioactive compounds discovered to date.1 The majority of microbial drug discovery research has focused on actinomycetes, in particular strains of the chemically prolific genus Streptomyces. Drug discovery efforts from actinomycetes, however, have been in decline, in part because of the relatively high frequency of the isolation of known compounds. To overcome this problem, extensive attempts… CONTINUE READING