Catecholamines and memory: Enhanced verbal learning during l-DOPA administration

  title={Catecholamines and memory: Enhanced verbal learning during l-DOPA administration},
  author={Dennis L. Murphy and George M. Henry and H. Martin Weingartner},
Verbal learning was measured during the administration of l-DOPA in large oral doses to depressed patients. Longer-term memory on two different tasks improved during treatment, while short-term memory (immediate recall) was unaffected. In contrast, the catecholamine synthesis inhibitor α-methyl-p-tyrosine did not alter either memory process. The effects of l-DOPA on learning may be related to increased arousal produced by this drug. 


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