Catecholamines and ascorbic acid as stimulators of bovine ovarian oxytocin secretion.

@article{Luck1987CatecholaminesAA,
  title={Catecholamines and ascorbic acid as stimulators of bovine ovarian oxytocin secretion.},
  author={M. Luck and B. Jungclas},
  journal={The Journal of endocrinology},
  year={1987},
  volume={114 3},
  pages={
          423-30
        }
}
The effects of catecholamines and ascorbic acid on cultured bovine granulosa cells have been examined to assess their possible role in the initiation and maintenance of luteal oxytocin secretion. The actions of these agents have also been compared with the previously reported ability of follicular theca tissue to enhance oxytocin secretion. Using granulosa cells cultured in serum-supplemented medium, we observed a highly significant enhancement of oxytocin secretion in the presence of… Expand
Enhanced secretion of oxytocin from bovine granulosa cells treated with adrenal steroids.
  • M. Luck
  • Biology, Medicine
  • Journal of reproduction and fertility
  • 1988
TLDR
It is concluded that cortisol may directly stimulate the secretion of ovarian oxytocin in the cow and that granulosa cells may respond in such a way as to smooth out the effects of short-term fluctuations in cortisol concentration. Expand
Beta adrenoceptors mediate the catecholamine-induced stimulation of oxytocin secretion from cultured bovine granulosa cells
TLDR
It is concluded that, during luteinization, the long-term response of bovine granulosa cells to stimulation induced by catecholamines is mediated through beta- rather than alpha-adrenoceptors. Expand
The effect of oxytocin on progesterone secretion and of PGF2α on oxytocin secretion from bovine luteal and granulosa cells in culture
Abstract Oxytocin had a variable effect on progesterone output from hCG-stimulated bovine luteal cells cultured for 12 h in vitro. In two out of eight experiments high doses of oxytocin (> 10−9 M)Expand
Chronic regulation of ovarian oxytocin and progesterone release by prostaglandins: opposite effects in bovine granulosa and early luteal cells.
  • C. McArdle
  • Biology, Medicine
  • The Journal of endocrinology
  • 1990
TLDR
The results reveal that the effects of prostaglandins on oxytocin release are dependent on both the developmental stage of the target tissue and on the presence of other regulators of cellular differentiation, and suggest that the increase in responsiveness to insulin and IGF-I, which appears to accompany luteinization in the cow, may be an effect of prostglandins produced locally during the peri-ovulatory period. Expand
Ovarian oxytocin and progesterone are secreted independently of one another
  • M. Luck
  • Biology, Medicine
  • Molecular and Cellular Endocrinology
  • 1988
TLDR
It is concluded that oxytocin and progester one can be independently secreted and that progesterone regulates neither its own secretion nor that of oxytocIn. Expand
Greatly elevated and sustained secretion of oxytocin by bovine granulosa cells in serum-free culture.
  • M. Luck
  • Biology, Medicine
  • The Journal of experimental zoology
  • 1989
TLDR
The results indicate that neither serum nor gonadotrophins are required for in vitro differentiation of bovine granulosa cells and that addition of serum may attenuate subsequent hormone secretion. Expand
Effects of gonadotropins, insulin and insulin-like growth factor I on ovarian oxytocin and progesterone production
TLDR
The data suggest that gonadotropins regulate oxytocin synthesis and release and that these effects are amplified by insulin or IGF-I acting via their own receptors. Expand
Biochemical and endocrine aspects of oxytocin production by the mammalian corpus luteum
  • F. Stormshak
  • Biology, Medicine
  • Reproductive biology and endocrinology : RB&E
  • 2003
TLDR
A review of the current state of knowledge of oxytocin production by the preovulatory follicle and corpus luteum is presented and evidence is presented for potential autocrine/paracrine actions of Oxytocin in regulating progesterone production by luteal and granulosa cells. Expand
The Effect of Oxytocin on Steroid Hormone Secretion by Isolated Porcine Follicular Cells in Tissue Culture
Abstract The effect of two doses (10 −7 M or 2 × 10 −7 M ) of oxytocin (OT) on progesterone, estradiol and androgen secretion by isolated follicular cell types: theca interna (T) and granulosa (G)Expand
Cholinergic stimulation, through muscarinic receptors, of oxytocin and progesterone secretion from bovine granulosa cells undergoing spontaneous luteinization in serum-free culture.
  • M. Luck
  • Biology, Medicine
  • Endocrinology
  • 1990
TLDR
It is concluded that bovine granulosa cells, exhibiting a luteinized phenotype in culture, are responsive to cholinergic agonists in a specific and saturable manner, indicating that cholinergy neurotransmitters may play a direct role in the regulation of ovarian function in the ruminant. Expand
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