Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea.

@article{Kelly2010CatecholaminesAA,
  title={Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea.},
  author={Andrea True Kelly and Shayne Dougherty and Andrew J. Cucchiara and Carole L. Marcus and Lee Jay Brooks},
  journal={Sleep},
  year={2010},
  volume={33 9},
  pages={1185-91}
}
INTRODUCTION Obstructive sleep apnea (OSA) has been implicated in the pathophysiology of metabolic syndrome. Its contribution to insulin resistance is complicated by obesity and puberty. We hypothesized that OSA is associated with worse insulin resistance and lower adiponectin after adjustment for obesity and puberty and that catecholamines might mediate these changes. METHODS Normal controls and children with suspected OSA were recruited and categorized as pubertal or prepubertal. Overnight… CONTINUE READING