Catecholamine release and potentiation of thromboxane A2 production by nicotine in the greyhound

@article{Dusting1986CatecholamineRA,
  title={Catecholamine release and potentiation of thromboxane A2 production by nicotine in the greyhound},
  author={G. Dusting and D. M. Li},
  journal={British Journal of Pharmacology},
  year={1986},
  volume={87}
}
  • G. Dusting, D. M. Li
  • Published 1986
  • Chemistry, Medicine
  • British Journal of Pharmacology
  • 1 Thromboxane A2 was generated by infusing arachidonic acid (2.5 μg ml−1) into an extra‐corporeal circuit of blood withdrawn from anaesthetized dogs, and assayed on a blood‐bathed bioassay cascade of porcine and bovine coronary artery strips, chick rectum and rat stomach strip. All tissues except chick rectum were treated with phentolamine and propranolol to abolish direct effects of catecholamines. 2 The arachidonate‐induced contractions of artery strips were abolished by a thromboxane… CONTINUE READING
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