Catechol releases iron(III) from ferritin by direct chelation without iron(II) production.

Abstract

It has been traditionally considered that catechols release iron from ferritin by reduction to iron(II), which diffuses through the ferritin channels into the intracellular milieu where it participates in the Fenton reaction, producing highly toxic hydroxyl radicals. However, in the present work we have proved that the mechanism of the release of iron from… (More)

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Cite this paper

@article{Snchez2005CatecholRI, title={Catechol releases iron(III) from ferritin by direct chelation without iron(II) production.}, author={Purificaci{\'o}n Gacto S{\'a}nchez and N. I. Perotti de G{\'a}lvez and Enrique Colacio and Elena Mi{\~n}ones and Jose M Dominguez-Vera}, journal={Dalton transactions}, year={2005}, volume={4}, pages={811-3} }