Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder.

@article{Rotondo2002CatecholOS,
  title={Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder.},
  author={Alessandro Rotondo and Chiara M Mazzanti and Liliana Dell'osso and Paola Rucci and Patrick H. Sullivan and Siham Bouanani and Chiara Gonnelli and David Goldman and Giovanni Battista Cassano},
  journal={The American journal of psychiatry},
  year={2002},
  volume={159 1},
  pages={23-9}
}
OBJECTIVE Genetic epidemiologic and clinical data suggest that comorbid panic disorder may define a subtype of bipolar disorder. Comorbid panic disorder might thereby influence the strength of association between bipolar disorder and genes that have been implicated in bipolar disorder on the basis of their function in monoamine neurotransmission and previously reported linkage results. Polymorphic markers at catechol O-methyltransferase (COMT), serotonin transporter (5-HTT), and tryptophan… CONTINUE READING

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Turk psikiyatri dergisi = Turkish journal of psychiatry • 2007
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